"Third places" and social interaction in deprived neighbourhoods in Great Britain

This paper explores social interaction in local ‘public’ social spaces such as local shops, pubs, cafés, and community centres in deprived neighbourhoods. More specifically, it examines the importance, role and function of these places, which have been described by Oldenberg and Brissett (Qual Sociol 5(4):265–284, 1982), Oldenburg (Urban design reader. Architectural Place, Oxford, 2007) as being “third places” of social interaction after the home (first) and workplace (second). It does so by drawing on data gleaned from in-depth interviews with 180 residents in six deprived areas neighbourhoods across Great Britain, conducted as part of a study of the links between poverty and place funded by the Joseph Rowntree Foundation. The paper notes that local third places are an important medium for social interaction in these areas, although their importance appears to vary by population group. It notes that shops appear to be a particularly important social space. It also identifies some of the barriers to social interaction within third places and concludes by highlighting some of the key implications for policy to emerge from the research

Deterministic continutation of stochastic metastable equilibria via Lyapunov equations and ellipsoids

Numerical continuation methods for deterministic dynamical systems have been one of the most successful tools in applied dynamical systems theory. Continuation techniques have been employed in all branches of the natural sciences as well as in engineering to analyze ordinary, partial and delay differential equations. Here we show that the deterministic continuation algorithm for equilibrium points can be extended to track information about metastable equilibrium points of stochastic differential equations (SDEs). We stress that we do not develop a new technical tool but that we combine results and methods from probability theory, dynamical systems, numerical analysis, optimization and control theory into an algorithm that augments classical equilibrium continuation methods. In particular, we use ellipsoids defining regions of high concentration of sample paths. It is shown that these ellipsoids and the distances between them can be efficiently calculated using iterative methods that take advantage of the numerical continuation framework. We apply our method to a bistable neural competition model and a classical predator-prey system. Furthermore, we show how global assumptions on the flow can be incorporated - if they are available - by relating numerical continuation, Kramers' formula and Rayleigh iteration.Comment: 29 pages, 7 figures [Fig.7 reduced in quality due to arXiv size restrictions]; v2 - added Section 9 on Kramers' formula, additional computations, corrected typos, improved explanation

Put on your poker face? Neural systems supporting the anticipation for expressive suppression and cognitive reappraisal

It is a unique human ability to regulate negative thoughts and feelings. Two well-investigated emotion-regulation strategies (ERSs), cognitive reappraisal and expressive suppression, are associated with overlapping prefrontal neural correlates, but differ temporally during the emotion-generation process. Although functional imaging studies have mainly investigated these ERS as a reaction to an emotion-inducing event, the intention to regulate upcoming negative emotions might already be associated with differences in neural activity. Hence, event-related functional magnetic resonance imaging was recorded in 42 participants while they completed an emotion-regulation paradigm. During this task, participants were instructed to proactively prepare to use a specific ERS knowing that a negative, high-arousing image would appear after the preparation period. As expected, the results demonstrated prefrontal and parietal activation while participants were suppressing or reappraising their emotions (family-wise error (FWE)-corrected). The intention to suppress emotions was associated with increased activation in the right inferior frontal gyrus, bilateral putamen, pre-supplementary motor area and right supramarginal gyrus (FWE-corrected). This enhanced proactive inhibitory control: (i) predicted decreased motoric activity during the actual suppression of emotional expressions and (2) trended toward a significant association with how successfully participants suppressed their emotions. However, neural correlates of preparatory control for cognitive reappraisal were not observed, possibly because contextual cues about the upcoming emotional stimulus are necessary to proactively start to cognitively reinterpret the situation

Use of control umbilicals as a deployment mode for free flying telerobotic work systems

Work to date on telerobotic work systems for use in space generally consider two deployment modes, free flying, or fixed within a limited work envelope. Control tethers may be employed to obtain a number of operational advantages and added flexibility in the basing and deployment of telerobotic work systems. Use of a tether allows the work system to be separated into two major modules, the remote work package and the control module. The Remote Work Package (RWP) comprises the free flying portion of the work system while the Control Module (CM) remains at the work system base. The chief advantage of this configuration is that only the components required for completion of the work task must be located at the work site. Reaction mass used in free flight is stored at the Control module and supplied to the RWP through the tether, eliminating the need for the RWP to carry it. The RWP can be made less massive than a self contained free flying work system. As a result, reaction mass required for free flight is lower than for a self contained free flyer

Dependence of Galaxy Shape on Environment in the Sloan Digital Sky Survey

Using a sample of galaxies from the Sloan Digital Sky Survey (SDSS) Data Release 4, we study the trends relating surface brightness profile type and apparent axis ratio to the local galaxy environment. We use the SDSS parameter `fracDeV' to quantify the profile type. We find that galaxies with M_r > -18 are mostly described by exponential profiles in all environments. Galaxies with -21 < M_r < -18 mainly have exponential profiles in low density environments and de Vaucouleurs profiles in high density environments. The most luminous galaxies, with M_r < -21, are mostly described by de Vaucouleurs profiles in all environments. For galaxies with M_r < -19, the fraction of de Vaucouleurs galaxies is a monotonically increasing function of local density, while the fraction of exponential galaxies is monotonically decreasing. For a fixed surface brightness profile type, apparent axis ratio is frequently correlated with environment. As the local density of galaxies increases, we find that for -20 < M_r < -18, galaxies of all profile types become slightly rounder, on average; for -22 < M_r < -20, galaxies with exponential profiles tend to become flatter, while galaxies with de Vaucouleurs profiles become rounder; for M_r < -22, galaxies with exponential profiles become flatter, while the de Vaucouleurs galaxies become rounder in their inner regions, yet exhibit no change in their outer regions. We comment on how the observed trends relate to the merger history of galaxies.Comment: 23 pages, 7 figures, accepted by Ap

Increased signaling entropy in cancer requires the scale-free property of protein interaction networks

One of the key characteristics of cancer cells is an increased phenotypic plasticity, driven by underlying genetic and epigenetic perturbations. However, at a systems-level it is unclear how these perturbations give rise to the observed increased plasticity. Elucidating such systems-level principles is key for an improved understanding of cancer. Recently, it has been shown that signaling entropy, an overall measure of signaling pathway promiscuity, and computable from integrating a sample's gene expression profile with a protein interaction network, correlates with phenotypic plasticity and is increased in cancer compared to normal tissue. Here we develop a computational framework for studying the effects of network perturbations on signaling entropy. We demonstrate that the increased signaling entropy of cancer is driven by two factors: (i) the scale-free (or near scale-free) topology of the interaction network, and (ii) a subtle positive correlation between differential gene expression and node connectivity. Indeed, we show that if protein interaction networks were random graphs, described by Poisson degree distributions, that cancer would generally not exhibit an increased signaling entropy. In summary, this work exposes a deep connection between cancer, signaling entropy and interaction network topology.Comment: 20 pages, 5 figures. In Press in Sci Rep 201

The relation between SAR and the electromagnetic field distribution for heterogeneous exposure conditions

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Ultrafast spatio-temporal dynamics of terahertz generation by ionizing two-color femtosecond pulses in gases

We present a combined theoretical and experimental study of spatio-temporal propagation effects in terahertz (THz) generation in gases using two-color ionizing laser pulses. The observed strong broadening of the THz spectra with increasing gas pressure reveals the prominent role of spatio-temporal reshaping and of a plasma-induced blue-shift of the pump pulses in the generation process. Results obtained from (3+1)-dimensional simulations are in good agreement with experimental findings and clarify the mechanisms responsible for THz emission

Measurements of the reverse current of highly irradiated silicon sensors to determine the effective energy and current related damage rate

The reverse current of irradiated silicon sensors leads to self heating of the sensor and degrades the signal to noise ratio of a detector. Precise knowledge of the expected reverse current during detector operation is crucial for planning and running experiments in High Energy Physics. The dependence of the reverse current on sensor temperature and irradiation fluence is parametrized by the effective energy and the current related damage rate, respectively. In this study 18 n-in-p mini silicon strip sensors from companies Hamamatsu Photonics and Micron Semiconductor Ltd. were deployed. Measurements of the reverse current for different bias voltages were performed at temperatures of −32 ° C, −27 ° C and −23 ° C. The sensors were irradiated with reactor neutrons in Ljubljana to fluences ranging from 2×1014neq∕cm2 to 2×1016neq∕cm2 . The measurements were performed directly after irradiation and after 10 and 30 days of room temperature annealing. The aim of the study presented in this paper is to investigate the reverse current of silicon sensors for high fluences of up to 2×1016neq∕cm2 and compare the measurements to the parametrization models

On the use of blow up to study regularizations of singularities of piecewise smooth dynamical systems in R3\mathbb{R}^3

In this paper we use the blow up method of Dumortier and Roussarie \cite{dumortier_1991,dumortier_1993,dumortier_1996}, in the formulation due to Krupa and Szmolyan \cite{krupa_extending_2001}, to study the regularization of singularities of piecewise smooth dynamical systems \cite{filippov1988differential} in $\mathbb R^3$. Using the regularization method of Sotomayor and Teixeira \cite{Sotomayor96}, first we demonstrate the power of our approach by considering the case of a fold line. We quickly recover a main result of Bonet and Seara \cite{reves_regularization_2014} in a simple manner. Then, for the two-fold singularity, we show that the regularized system only fully retains the features of the singular canards in the piecewise smooth system in the cases when the sliding region does not include a full sector of singular canards. In particular, we show that every locally unique primary singular canard persists the regularizing perturbation. For the case of a sector of primary singular canards, we show that the regularized system contains a canard, provided a certain non-resonance condition holds. Finally, we provide numerical evidence for the existence of secondary canards near resonance.Comment: To appear in SIAM Journal of Applied Dynamical System